Author: myhouseman

Classification • Selective vs non-selective• Vasodilating vs non-vasodilating=====• First generation (e.g. propranolol), Second generation (e.g. Acebutolol, Atenolol, Metoprolol, Bisoprolol, Esmolol), Third generation – vasodilating • Third generation, ß1 selective (e.g. Nebivolol, Betaxolol)• Third generation, non selective — ß1, ß2, α1 (e.g. Labetalol, Carvedilol) • Selective — ß1 > ß2 (e.g. Atenolol, Metoprolol) ** ß-blocker is […]

Classifications: (i) Thiazide e.g. (ii) Thiazide-like diuretics e.g. chlorthalidone (CTD), indapamide Mechanisms of Action Blocks Na+-Cl− co-transporter at the beginning of distal convoluted tubule → inhibits odium re absorption Natriuretics would alter long term sodium balance → reduced peripheral vascular resistance & sustained BP reduction As more sodium reaching collecting duct, hypokalaemia occurs Indications Hypertension […]