Last Updated on October 10, 2022
Introduction
• Third generation beta-blocker, non-selective
Advantages
• Effective in hypertension
• Improves mortality & morbidity in patients with heart failure
• No adverse effect on insulin resistance & lipid metabolism
Precaution
• Safety in pregnancy not established
Dosage
Notes: different dosage for patients with heart failure / angina
Hypertension
• Starting dose: 12.5 mg OD
• Recommended maximum daily dose: 50 mg OD / in divided dose if necessary
Heart failure
• Starting dose: 3.125 mg BD
• Target dose: 25 mg BD (50 mg if >85 kg)