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Serum Osmolality / Osmolal Gap

Last Updated on May 15, 2022

Introduction

Osmolal gap = measured serum osmolality – calculated serum osmolality
• Calculated serum osmolality = 2[Na+] + Glucose + Urea
• Marked increased osmolal gap (>25 mOsm) is pathognomonic of toxic alcohol poisoning!

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